MP46-18 PATIENTS REPORT SATISFACTION/REGRET FOLLOWING FOCAL THERAPY FOR LOCALIZED PROSTATE CANCER: A PROSPECTIVE MULTICENTER EVALUATION

نویسندگان

چکیده

You have accessJournal of UrologyProstate Cancer: Localized: Ablative Therapy (MP46)1 Sep 2021MP46-18 PATIENTS REPORT SATISFACTION/REGRET FOLLOWING FOCAL THERAPY FOR LOCALIZED PROSTATE CANCER: A PROSPECTIVE MULTICENTER EVALUATION Alireza Ghoreifi, Masatomo Kaneko, Samuel Peretsman, Atsuko Iwata, Aliasger Shakir, Dordaneh Sugano, Jie Cai, Giovanni Cacciamani, Daniel Park, Osamu Ukimura, Duke Bahn, Inderbir Gill, and Andre Luis Abreu GhoreifiAlireza Ghoreifi More articles by this author , KanekoMasatomo Kaneko PeretsmanSamuel Peretsman IwataAtsuko Iwata ShakirAliasger Shakir SuganoDordaneh Sugano CaiJie Cai CacciamaniGiovanni Cacciamani ParkDaniel Park UkimuraOsamu Ukimura BahnDuke Bahn GillInderbir Gill AbreuAndre View All Author Informationhttps://doi.org/10.1097/JU.0000000000002067.18AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The objective is evaluate the treatment decision satisfaction regret among patients who underwent Focal (FT) for localized prostate cancer (PCa) with high-intensity focused ultrasound (HIFU) or cryoablation (CRYO). METHODS: We identified consecutive hemi-gland HIFU CRYO FT as primary PCa at three US institutions (IRB# HS-17-00749). survey validated questionnaires was mailed between February December 2020, including: 5-question Decision Regret Scale (DRS); International Prostate Symptom Score (IPSS); Index Erectile Function (IIEF-5). Potency defined IIEF-5 ≥ 18. score calculated based on 5 items DRS (Figure). Agreement each item measured a 5-point scale final converted 0-100 scale. 26. Multivariable logistic regression models were applied assess baseline post-FT predictors regret. Statistically significant if p<0.05. RESULTS: Out 236 patients, 143 (61%) responded (71/116 72/120 CRYO). Baseline characteristics similar responders no-responders. For responders, median (IQR) follow-up 43 (26-68) months. rate 19.6%, being 23.6% vs. 15.5% (OR 1.7, p=0.22). Figure shows details patients’ responses question. Higher PSA nadir 1.48, 95%CI 1.1-2, p=0.009) post FT, presence biopsy 3.98, 1.5-10.6, p=0.006), higher IPSS after 1.18, 1.01-1.04, p=0.03), de-novo impotence 6.67, 1.57-27, p=0.03) independent CONCLUSIONS: therapy well-accepted patients. nadir, biopsy, post-operative IPSS, are Source Funding: None © 2021 American Urological Association Education Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e820-e821 Advertisement Copyright & Permissions© Inc.MetricsAuthor Information Expand Loading ...

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Focal Therapy in the Management of Prostate Cancer: An Emerging Approach for Localized Prostate Cancer

A widespread screening with prostate-specific antigen (PSA) has led increased diagnosis of localized prostate cancer along with a reduction in the proportion of advanced-stage disease at diagnosis. Over the past decade, interest in focal therapy as a less morbid option for the treatment of localized low-risk prostate cancer has recently been renewed due to downward stage migration. Focal therap...

متن کامل

MRI evaluation following partial HIFU therapy for localized prostate cancer: A single-center study.

OBJECTIVE To evaluate the value of MRI for surveillance of primary hemi-HIFU therapy for localized PCa in a single-center. PATIENTS AND METHODS Patients with localized prostate cancer were treated with hemi-HIFU from October 2009 to March 2014. All patients performed MRI before focal therapy, the reader was blinded to the treatment. Oncological failure was defined as positive biopsy or bioche...

متن کامل

Focal Therapy for Prostate Cancer

The prostate cancer pathway from screening and diagnosis through to treatment has recently been critically questioned in light of level 1 evidence pointing toward pathway-related harms that may outweigh the benefits in many men. As a consequence, guidelines on screening in prostate cancer have recommended limiting the systematic use of screening based on prostate-specific antigen (PSA) testing ...

متن کامل

Focal therapy in prostate cancer-report from a consensus panel.

PURPOSE To establish a consensus in relation to case selection, conduct of therapy, and outcomes that are associated with focal therapy for men with localized prostate cancer. MATERIAL AND METHODS Urologic surgeons, radiation oncologists, radiologists, and histopathologists from North America and Europe participated in a consensus workshop on focal therapy for prostate cancer. The consensus p...

متن کامل

Focal Therapy in Prostate Cancer—Report from a Consensus Panel

Purpose: To establish a consensus in relation to case selection, conduct of therapy, and outcomes that are associated with focal therapy for men with localized prostate cancer. Material and Methods: Urologic surgeons, radiation oncologists, radiologists, and histopathologists from North America and Europe participated in a consensus workshop on focal therapy for prostate cancer. The consensus p...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: The Journal of Urology

سال: 2021

ISSN: ['0022-5347', '1527-3792']

DOI: https://doi.org/10.1097/ju.0000000000002067.18